European Bioinformatics Institute | EMBL-EBI

www.ebi.ac.uk

1 Job

826 Employees

About the Company

Working at EMBL-EBI gives you the opportunity to focus your energy and skills on something that really matters: using technology to contribute to discoveries that benefit humankind. We empower researchers everywhere to realise the potential of 'big data' in biology, and build sophisticated tools for exploring life at the atomic level.

Listed Jobs

Company Name: European Bioinformatics Institute | EMBL-EBI
Job Title: Bioinformatician
Job Description: **Job title** Bioinformatician **Role Summary** Design, develop, and maintain scalable bioinformatics pipelines that produce reference‑quality gene annotations for human and mouse genomes. Work closely with genomic data analysts to integrate primary sequencing data, validate gene models, and support automated annotation workflows used globally in research and clinical genomics. **Expectations** - Deliver robust, version‑controlled code in a release‑driven environment. - Collaborate with international partners and cross‑functional teams. - Communicate complex biological and computational concepts clearly to both technical and non‑technical audiences. **Key Responsibilities** - Develop and deploy annotation pipelines for protein‑coding and non‑coding RNA genes. - Integrate cutting‑edge primary data (e.g., RNA‑seq, Ribo‑seq, long‑read sequencing) to refine gene structure and function. - Extend GENCODE annotation to human and mouse pangenomes and generate training datasets for machine‑learning initiatives. - Maintain relational database schemas and perform efficient queries for annotation data. - Operate within a version‑controlled codebase, ensuring code quality and documentation. - Coordinate releases, troubleshoot pipeline failures, and optimize computational performance. - Participate in user training and provide technical support for annotation methods. **Required Skills** - Proficiency in scripting/programming languages (Python, Perl, or similar). - Experience designing and maintaining large‑scale data pipelines (e.g., Nextflow, Snakemake, WDL). - Strong understanding of genome annotation principles and DNA/RNA sequencing methods. - Knowledge of relational databases (SQL) and schema design. - Familiarity with compute clusters, job scheduling, and performance tuning. - Basic machine‑learning concepts and ability to generate training data. - Excellent problem‑solving, attention to detail, and independent work capability. - Effective communication and teamwork skills in an international setting. **Required Education & Certifications** - MSc, PhD, or equivalent in Computer Science, Bioinformatics, Genetics, or related field. - Demonstrated experience writing, understanding, and maintaining complex code.

England, United kingdom

On site

10-01-2026