Job Specifications
Company Description
UHN is Canada's #1 hospital and the world's #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.
UHN's vision is to build A Healthier World and it's only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.
www.uhn.ca
Job Description
Union: Non-Union
Number of Vacancies: 1
Site: All Sites
Department: Laboratory Medicine Program, Advanced Diagnostics
Reports to: Senior Manager, Advanced Diagnostics
Hours: 37.5 hours per week
Shifts: All Shifts 24/7
Status: Temporary Full Time (1 year)
Closing Date: October 8, 2025
Position Summary
Join UHN's Laboratory Medicine Program, Canada's largest hospital diagnostic lab and a global leader in academic labs. With over 30 million tests per year and 1,300 outpatients served daily, we are at the forefront of pathology and clinical testing. Embrace innovation and contribute to ground-breaking research, education, and exemplary service. Join our dynamic team of 700 dedicated staff and play a pivotal role in shaping the future of laboratory medicine.
As an integral member of the Clinical Genomics team, the Annotation Analyst plays a key role in supporting the efforts of the Clinical Genome Diagnostics laboratory.
Duties
Utilizing software tools, databases and primary literature to investigate the clinical relevance of variants detected by genetic methods including next-generation sequencing (NGS)
Drafting concise variant interpretations
Utilizing practical and theoretical knowledge for the analysis of NGS and other laboratory data, including somatic and germline testing
Completing required database and reporting activities related to variant analyses
Completing assigned workload in a manner to ensure the efficient operation of the clinical laboratory
Participating in molecular profiling test development activities with laboratory technologists
Maintaining quality control standards in assigned area
Participating in communication activities to maintain and continually enhance the co-operation and coordination of services with other laboratory staff and with external lab clients
Participating in professional development, teaching/education activities, safety and quality improvement programs to ensure excellence in the provision of services
Adhering to Hospital and departmental mission and value statements while maintaining patient confidentiality
Qualifications
Master's degree in Molecular Genetics or related discipline required at minimum
6 months minimum of relevant experience required
Knowledge of and experience with molecular genetic variant assessment techniques
Knowledge of and experience with the use of genetic databases / resources and software (e.g. HGMD, COSMIC, gnomAD, cBioPortal, CICiC, ClinVar)
Knowledge of and experience with the theory and application of NGS platforms and NGS analysis
Knowledge of the theory and practice of current NGS laboratory procedures, instruments, equipment and special techniques
Excellent problem recognition and problem solving skills
Effective organizational, time management and prioritization skills
Excellent verbal and written communication skills
Ability to learn quickly, take in and distill large amounts of information and apply scientific knowledge
Scientific curiosity and interest to stay on top of emerging scientific data and trends as it pertains to the role
Demonstrated ability to take initiative, multitask and think critically
Ability to work independently and with cross-functional team members
Additional Information
Why join UHN?
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.
Competitive offer packages
Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
Close access to Transit and UHN shuttle service
A flexible work environment
Opportunities for development and promotions within a large organization
Additional perks (multiple corporate discounts including:
About the Company
University Health Network (UHN) is Canada's largest research hospital, which includes Toronto General and Toronto Western Hospitals, Princess Margaret Cancer Centre, the Toronto Rehabilitation Institute and the Michener Institute for Education at UHN. The scope of research and complexity of cases at UHN has made it a national and international source for research, education and patient care.
UHN is a research hospital affiliated with the University of Toronto, with major research in cardiology, transplantation, neuroscienc...
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